Thursday, February 9, 2017

On Monday, scientists from the Stanford University School of Medicine announced the invention of a new diagnostic tool that can sort cells by type: a tiny printable chip that can be manufactured using standard inkjet printers for possibly about one U.S. cent each. Lead researchers say this may bring early detection of cancer, tuberculosis, HIV and malaria to patients in low-income countries, where the survival rates for illnesses such as breast cancer can be half those of richer countries.

Existing methods tend to identify cell types using fluorescent or magnetic labels, which take time to attach, but this platform uses the phenomenon of dielectrophoresis: because different kinds of cells have different levels of receptivity to electrical fields, a trait called polarizability, when an electric potential gradient is activated around the chip, different cells are pulled in different directions at different speeds. This allows doctors to diagnose cancer by determining the number of tumor cells in a patient’s blood sample. Different chips can be printed to diagnose different diseases.

Physically, the scientists say, the system has two parts. Cells are held in a clear microfluidic chamber made of silicone. The chip itself is an electronic strip that can be printed onto flexible polyester. Most lab-on-a-chip devices must be manufactured by professional staff in specialized facilities called clean rooms and can take weeks, but the chip component of this system can be made almost anywhere in as little as twenty minutes. The chips cost approximately one U.S. cent to produce (US$0.01) and can be reused. For comparison, a standard flow cytometry machine can cost US$100,000 to purchase.

“Enabling early detection of diseases is one of the greatest opportunities we have for developing effective treatments,” said lead author and electrical engineer Dr. Rahim Esfandyarpour. “Maybe $1 in the U.S. doesn’t count that much, but somewhere in the developing world, it’s a lot of money.”

Senior author Dr. Ron Davis of the Stanford University Genome Technology Center compared this invention to that of low-cost genome sequencing, which helped lead to personalized medicine.

The findings appeared in the Proceedings of the National Academy of Sciences on Monday.

Wednesday, November 9, 2005

At least three explosions hit US-owned hotels in Amman this evening, killing at least 57 people and wounding at least 245 others.

The first of the apparently coordinated suicide bombings occurred at 8.50 pm (1850 UTC) at the Grand Hyatt hotel in the Jordanian capital. It was followed by explosions at the Radisson SAS and the Days Inn. The hotels are particularly popular with American and Israeli tourists. At least one American was killed, and at least two others were wounded. They were not identified due to the condition on anonymity in the embassy.

The bomb at the Grand Hyatt hotel apparently went off in the lobby; the bomb at the Radisson SAS exploded in a wedding hall packed with around 300 people. Most of the casualties are believed to be Jordanian.

Jordanian King Abdullah II has condemned the bombings and announced that “justice will pursue the criminals”.

Islamic fundamentalist group Al-Qaeda, led by militant Abu Musab al-Zarqawi, is said to have claimed responsibility for the attacks on their website. The news was reported by several news outlets, but the authenticity of the claim has not yet been verified.

Tuesday, February 5, 2008

The fourth day of New York Fashion Week debuted few daring designs even from designers known for such work. With few exceptions, the overwhelming theme was “old is new” and that the ’70s were even more in fashion than the shows on Sunday suggested. Among the designers to unveil their Fall 2008 lines on Monday were Oscar de la Renta, Carolina Herrera, Betsey Johnson, Proenza Schouler and a rejuvenated Halston line, under the direction of designer Marco Zanini.

Both global warming and the slowing economy have been cited as reasons for the overwhelming use of lighter fabrics over heavier attire. Also, retro designs and continuing trends have been used in effort to save money, like the tights that were expected to go out of fashion this year. Even in the glamorous world of high-end fashion, money has been tight, and with the world economies in a collective downturn, major designers have been more wary of continuing to churn out the stream of couture designs that past Fashion Weeks have seen.

Proenza Schouler’s show took the ’70s retro theme to a fever pitch, liberally using bows on designs and debuting more retro-era wide-legged pants that were first seen in Sunday’s shows. Zanini’s Halston label also brought back the ’70s, resurrecting old designs that the founder of the line made famous. Since the designer Halston’s death in 1990, many designers have tried to take the label in different directions. Zanini’s unveiling on Monday brought the line back to its Studio 54 roots, while using trenchcoats, sheer fabrics, and cardigans to finish the ensembles with a modern twist.

Betsey Johnson also debuted old and new styles on Monday, to celebrate the 30th anniversary of her fashion label. Copies of her original 1978 one-piece bathing suit as well as some early 1980s fashions started off the show. Her new pieces, such as animal print leggings coupled with a short twill jacket, were perceived as very skintight and criticized for not representing more fuller figures. Johnson brushed off the criticism, noting, “It’s tighter and sexier, but I still believe the girl brings the sex to the clothes…You won’t look sexy in a tight, below-the-knee skirt if you don’t feel good in it.”

The lone daring designer for the day was Carolina Herrera, who discarded the furs she promoted in the Fall 2007 show to focus on a Peter Pan theme, with earth tones and bird feathers. To further the “flying Peter Pan” motif, models donned such designs as a chiffon dress with ostrich feathers and a taffeta gown with a feather waistband.

Oscar de la Renta opted for more traditional blacks, golds and grays, debuting lines for men and women in fabrics he is familiar with. Men were outfitted in tweed while women were fitted in dresses that experimented with embroidery and tulle, both shades of past collections.

New York Fashion Week runs until Friday. Among others, labels Badgley Mischka, Diesel, and Vivienne Tam unveil their newest collections on Tuesday.

Wednesday, August 29, 2007

An English lawyer has pleaded guilty to perverting the course of justice. He faked a legal judgment and sent it to a father who was pleading in Taunton family court to be able to remain involved in his child’s upbringing. The lawyer, London barrister Bruce Hyman, now awaits his sentence. The judge indicated that he could receive a prison sentence. Bruce Hyman is well-known in media circles, having produced The Hitchhiker’s Guide to the Galaxy on BBC Radio. He also produced a series with Clive Anderson, at Above the Title Productions, called Unreliable Evidence.

The father, a former City financier, had attended a series of court hearings in order to make suitable arrangements to see his child following an acrimonious divorce. Shortly before one of these hearings he received an email, ostensibly from a self-help group to which he belonged, which had attached a Court of Appeal case that appeared favourable to an application he had made for the judge to stand down from the case. The father, who was representing himself, duly showed the case to the judge. At this point, Bruce Hyman, the lawyer representing the former wife, claimed to the judge that the case was a forgery, which indeed it turned out to be.

After confirming that the self-help group had not sent him the email, the father then embarked on some detective work his own. The fraudulent email was traced via its header to a dial-up internet connection and a phone number belonging to a shop in London. The shop was able to recover CCTV footage which showed a man sending the email from an Apple laptop. The man turned out to be Bruce Hyman.

Sentencing of Hyman is due in Bristol Crown Court on the 19th of September.

Saturday, February 23, 2008

Wikinews held an exclusive interview with James Burns, one of the candidates for the Libertarian Party nomination for the 2008 U.S. presidential election.

Burns, the former chairman of the Nevada Libertarian Party, was asked if he thinks he has a good shot at winning the Libertarian nomination and ultimately the presidency. He replied, “My chances of winning are not all in my hands. I shall do my best, but it comes down to what others will do. What will you do?”

When asked about America’s shrinking middle class he said, “The economic policies of the US government are the cause our troubles. When I am President, the only economic policy I shall pursue is to be frugal with the funds of the United States.”

Burns believes that the President “is not ‘the leader of the free world,’ rather….a person who attempts to protect our rights to life, liberty, and the pursuit of happiness.”

Saturday, April 8, 2006

A Honolulu man who fell into the sewage-contaminated Ala Wai Yacht Harbor died Thursday night of a massive bacterial infection that caused the loss of one of his legs, septic shock, and ultimately organ failure.

Oliver Johnson, 34, a Honolulu mortgage broker, died between 9:15 and 9:30 p.m. HST Thursday (0715-0730 UTC Friday) when his family removed him from life support. On Friday, March 31, Johnson had apparently fallen into the waters of the Ala Wai Yacht Harbor, located at the mouth of the Ala Wai Canal on the western side of Waikiki.

At the time, the canal and surrounding beaches were contaminated by over 48 million gallons of untreated sewage. The extent to which the sewage spill contributed to Johnson’s symptoms remains unclear.

Johnson earlier reported that he had fallen accidentally into the harbor, then later indicated that he had been involved in a fight on board a boat and had been pushed or thrown into the harbor waters. A security guard at Johnson’s apartment reported that he was bloodied and soaking wet, and that he stumbled into the lobby and collapsed. Paramedics took Johnson to Straub Hospital where he was treated and released.

Johnson reported steadily worsening leg pain that weekend and was admitted to Queen’s Hospital on Sunday with breathing difficulties. Doctors that night amputated his left leg above the knee to try to halt the spread of the infection, and Johnson was placed in a medically induced coma.

Initially suspecting that Johnson had contracted streptococcus-caused necrotizing fasciitis, doctors later found that Johnson had contracted three different bacteria, two of which, vibrio vulnificus and aeromonas hydrophila, have flesh-eating properties. Despite the amputation, Johnson’s condition steadily worsened to the point where doctors said that his other leg and left arm would also have needed to be amputated to save his life.

An autopsy performed by the Honolulu medical examiner’s office reported that Johnson had suffered from massive organ failure caused by septic shock. The medical examiner noted that Johnson had a vulnificus infection on his foot and suffered from chronic alcoholic liver disease which may have contributed to the infection’s taking hold.

The Honolulu Police Department has opened a third-degree assault case; with Johnson’s death, homicide detectives are also investigating. State health officials are also investigating Johnson’s illness.

Johnson’s family has retained an attorney to investigate the causes surrounding his illness and death. It is not clear yet whether any legal action will be taken.

Wednesday, November 9, 2005

The Dover, Pennsylvania school board became the first to mandate inclusion of Intelligent Design in a public school biology curriculum. For this year’s November 8 election, Republicans fielded a pro-Intelligent Design slate of candidates including some returning candidates who had previously voted to include a statement about Intelligent Design in the biology curriculum. A mixed slate of Democrat and Republican candidates came forward as an alternative group of school board candidates, the Dover CARES coalition. They proposed to remove Intelligent Design from the biology curriculum but allow discussion of Intelligent Design in courses dealing with philosophy and comparative religion.

All eight open school board seats were won by Dover CARES coalition candidates. Two candidates who had previously voted as school board members to include intelligent design in the public school science curriculum received the fewest votes in Tuesday’s election. One of the newly elected board members is Bryan Rehm, a parent of a Dover school student. Rehm, along with ten other parents, initiated a law suit against the school board for its decision to insert Intelligent Design into the science curriculum.

In October 2004, the Dover school board decided that Intelligent Design is a scientific theory that should be mentioned in biology classes that include discussion of biological evolution as part of the course content. The board mandated that a statement should be read in those classes stating “Intelligent Design is an explanation of the origin of life,” and “The school leaves the discussion of the Origins of Life to individual students and their families.”

The school board’s statement on Intelligent Design directs students to the book Of Pandas and People as a source of information “for students who might be interested in gaining an understanding of what Intelligent Design actually involves.” This book is published by the Foundation for Thought and Ethics, a non-profit organization founded for the purpose of “promoting and publishing textbooks presenting a Christian perspective.”

Parents of some Dover public school students filed a lawsuit against the school board, charging that including the school board’s statement on Intelligent Design was an attempt to introduce religion into the science curriculum. The book Of Pandas and People says, “Intelligent design means that various forms of life began abruptly through an intelligent agency.” The original complaint in the law suit against the school board claimed that “Intelligent design is a non-scientific argument or assertion.”

The US District Court Judge John Jones, who heard the non-jury case, hopes to make his ruling by the end of the year. The evidence phase of the trial ended on November 4, 2005.

A local Dover newspaper, the York Daily Record, editorialized that Dover voters should take trial testimony into account during the general election when they could cast votes for school board members along with other elective offices.

Biology teachers in the Dover schools have refused to read the school board’s statement on Intelligent Design to students because the Pennsylvania state code for education states that “The professional educator may not knowingly and intentionally misrepresent subject matter.” In a letter to their administrator, the teachers stated their view that “Intelligent design is not science.” School administrators have been reading the school board’s Intelligent Design statement to students in Dover public schools.

Thursday, October 15, 2009

Falcon Heene, a 6-year-old boy from Fort Collins in the US state of Colorado, has been found safe and unharmed after earlier reports said he boarded an experimental balloon the family was building and then floated away. The Larimer County sheriff announced during a press conference at 6:11 p.m. that Heene was found hiding inside a box in the family’s attic above the garage.

Earlier reports had said that Heene might have been inside a box attached to the bottom of the balloon, something authorities were focusing part of their search on. However, there were conflicting reports as to whether or not there was anything else attached to the balloon. The New York Times reports that the small compartment present on the bottom of the balloon when it landed, was the alleged box.

“It [the box] was damaged. Basically, it was folded over and damaged,” said Larimer County sheriff spokeswoman, Kathy Messick to the Times.

The balloon landed south of Prospect Springs. Police stated that they were searching for Heene based on what his two other brothers told authorities. A witness had earlier said that he might have seen something fall off the balloon on Weld County Roads 28, 41 or 43. Authorities were also looking into the possibility that Heene was never inside the balloon at all, and that he was hiding somewhere in his neighborhood to avoid punishment. This ultimately turned out to be true.

Initial reports were that Heene allegedly climbed into the balloon in his backyard in Fort Collins at about 11:00 a.m. local time. He then detached the anchor and began to float away. Police later said in a press conference that the story came from Falcon’s two brothers. Local residents were able to snap pictures of the balloon. Shortly after, a news helicopter was able to locate the balloon, which was initially flying at an altitude of 7,000 feet.

The balloon was never meant to carry a human, according to Fort Collins police. “This balloon was never meant to actually carry anybody. It was just a family project they were working on. The little compartment where their son is in is very small and it’s not attached very well.”

The Heene family lives in Fort Collins. The boy’s father, Richard, is a storm chaser and scientist. One report said they were building the experimental balloon in an effort to help commuters get to work easier. Officials say it has the ability to fly at an altitude of 10,000 feet. It is reported to be about 20 feet long, covered in tinfoil and resembles a flying saucer. Richard and his wife Naomi previously appeared on an episode of the U.S. television show Wife Swap and Richard has appeared in several videos chasing storms and dust devils. One of those chases was previously featured on an ABC News report.